Cinnamic acid deriv. Your use of this website indicates your agreement to these terms and those published here. Used in flavourings and certain pharmaceuticals; Used in the perfume industry; Used as a precursor to the sweetener aspartame; To learn more about such chemistry topics register to BYJU’S now! Cinnamic acid is a known allelochemical that affects seed germination and plant root growth and therefore influences several metabolic processes. Cinnamic acid (C 9 H 8 O 2) is structurally similar and occurs in cinnamon, cloves, black pepper, coriander and turmeric. It is a member of styrenes and a member of cinnamic acids. We now show that cinnamic acid induces cytostasis and a reversal of malignant properties of human tumor cells in vitro. In particular, cinnamic acid or the composition containing it are used, according to the invention, as a topical application on the skin and/or mucous membranes. Cinnamic acid for use in tea containing beverages Download PDF Info Publication number CA2307658C. The kinetic behavior of cinnamic acids, their methyl esters, and two catechols 1−10 (ArOH) in the reaction with DPPH• in methanol and ethanol is not compatible with a reaction mechanism that involves hydrogen atom abstraction from the hydroxyl group of 1−10 by DPPH•. Other rarely utilized functions of cinnamic acid derivatives are as an antioxidant, in skin conditioning, hair conditioning, as a tonic and in antimicrobial activities. Type of substance Composition: mono-constituent substance Origin: organic Total tonnage band Total range: Intermediate Use Only REACH Registered as: INTERMEDIATE Submitted: Individual Submission Publication dates … Neochlorogenic acid. Understanding the phytochemical power of turmeric, Keep your skin healthy this summer with these natural moisturizers, Cognitive Effects and Dietary Restrictions May Soon Ease for PKU Sufferers, chemical reaction between benzaldehyde and acetic anhydride, production of methyl, ethyl, and benzyl esters, compoundâs potential in cancer intervention, may help pre-diabetic and diabetic patients, Glucophage – uses, health risks, and side effects at NaturalPedia.com, Norvasc – uses, health risks, and side effects at NaturalPedia.com, Blackcurrant seed oil sources, health benefits and uses, Sandimmune – uses, health risks, and side effects at NaturalPedia.com. Know about technical details of Cinnamaldehyde like: chemical name, chemistry structure, formulation, uses, toxicity, action, side effects and more at Pharmacompass.com. Molecular Weight 148.16 . The lack of data on cinnamic acid makes identifying the body systems that it supports difficult. risk assessment of related esters and alcohols of cinnamic acid and cinnamyl alcohol (see Table 1). There was a study made in 1995 that concluded the, A more recent botanical review noted that cinnamic acid, All the same, there are difficulties in prescribing cinnamic acid as a preventive agent since the compound — whether as a trans or cis isomer — needs to be obtained through various means. It can also be prepared by oxidation of cinnamaldehyde, condensation of benzal chloride and sodium acetate (followed by acid hydrolysis), and the Perkin reaction. Its uses for medicine have only been studied recently. See more. These esters are important components of perfumes. Stars This entity has been manually annotated by the ChEBI Team. Print infocard. In particular, 4-hydroxycinnamic acid, which … The ‘Substance identity’ section is calculated from substance identification information from all ECHA databases. It is created by the deamination of phenylalanine and it is then itself converted to any of the various polyphenols synthesized by plants. [4] It is also found in shea butter. Classified as an unsaturated carboxylic acid, it occurs naturally in a number of plants. It is also used as a precursor of the sweetener, aspartame.1 It has a role as a plant metabolite. As B. cinerea , P. expansum , and A. niger ( Sadeghi et al., 2013 ). Cinnamic acid is preferably used according to the invention. A major use is as a precursor to produce methyl cinnamate, ethyl cinnamate, and benzyl cinnamate for the perfume industry. When applied at low micromolar concentrations to Arabidopsis roots, c-CA stimulates both cell division and cell expansion in leaves. Cinnamic acid is a white crystalline hydroxycinnamic acid, which is slightly soluble in water. It exists as both a cis and a trans isomer, although the latter is more common. The process in which this type of cinnamic acid is synthesized ensures that the compound is removed from all its impurities. The acid can exist as both trans and cis isomers; however it is the cis form that most people use today as it can be easily derived from a chemical reaction between benzaldehyde and acetic anhydride. Assay: 98% Min. Some of them may become new cosmetic ingredients in the future. Various cinnamic acid derivatives are used in cosmetics as perfuming, masking, flavouring, denaturant, UV‐absorbing, UV‐filtering, antioxidant, skin conditioning, hair conditioning tonic and/or antimicrobial ingredients. It is used in the manufacture of methyl, ethyl, and benzyl esters for perfume industry. Cinnamic acid, a naturally occurring aromatic fatty acid of low toxicity, has a long history of human exposure. Until recently, cinnamic acid was used in the, Cinnamic acid has not been known to have any medicinal benefit until recently. It is obtained from oil of cinnamon, or from balsams such as storax. Regulatory process names 2 IUPAC names 4 Other identifiers 1 . This report uses data from animals and humans by various routes of exposure, but emphasizes the risk assessment for the use of related esters and alcohols of cinnamic acid and cinnamyl alcohol as fragrance ingredients. Cinnamic acid is used in the flavors, synthetic indigo and certain pharmaceuticals. It is an organic acid isolated from cinnamon bark or benzoin. Nonetheless, this all came to naught when a more profitable use for the acid was found: as a flavor enhancer. Cinnamic acid is composed of a series of trans-phenyl-3-propenoic acids. The compoundâs derivatives have thus far been used as flavor enhancers, with a specific variety acting as a precursor for the sweetener aspartame. All the same, there are difficulties in prescribing cinnamic acid as a preventive agent since the compound — whether as a trans or cis isomer — needs to be obtained through various means. It is a white crystalline compound that is slightly soluble in water, and freely soluble in many organic solvents. In conclusion, trans ‐cinnamic acid can be used as an environmentally friendly alternative additive to prevent and control primarily A. sobria, as well as other pathogenic bacteria such as A. salmonicida, V. anguillarum, V. crassostreae and Y. ruckeri. Formule: C₉H₈O ₂ Poids moléculaire: 148,16 g/mol Point d'ébullition: 300 °C (1013 hPa) Point de fusion: 131…134 °C Densité: 1,25 g/cm³ (4 °C) Numéro MDL: MFCD00004369 Numéro CAS: 140-10-3 EINECS: 205-398-1: Commander maintenant. Cinnamic acid has not been known to have any medicinal benefit until recently. Turmeric vs Curcumin: Whatâs the Difference and Which is Better? eCl@ss 39023931 . Cinnamic acid uses. Based on the available literature, this broad range of usage of cinnamic acid derivatives might be extended by skin lightening and anti‐ageing functions. [5] In 1890, Rainer Ludwig Claisen described the synthesis of ethyl cinnamate via the reaction of ethyl acetate with benzaldehyde in the presence of sodium as base. EC Number 205-398-1. A more recent botanical review noted that cinnamic acid may help pre-diabetic and diabetic patients. Substance identity Substance identity. CA2307658C CA 2307658 CA2307658A CA2307658C CA 2307658 C CA2307658 C CA 2307658C CA 2307658 CA2307658 CA 2307658 CA 2307658 A CA2307658 A CA 2307658A CA 2307658 C CA2307658 C CA 2307658C Authority CA Canada Prior art keywords ppm beverage acid tea cinnamic acid Prior art … Further research into this area is necessary. TLC and 1H NMR analysis confirm the purity of final product, without any cinnamic acid contamination, and thus it is not necessary to make any recrystallization. Cinnamic acid deriv. It is obtained from oil of cinnamon, or from balsams such as storax. It is sometimes called the parent polyphenol because all of the myriad polyphenol compounds synthesized by plants are derived from cinnamic acid 1. It is found in Cinnamomum cassia. It is a conjugate acid of a 3,4,5-Trihydroxycinnamic acid analytical standard provided with w/w absolute assay, to be used for quantitative titration. Cinnamic acid (C 9 H 8 O 2) is an organic acid isolated from cinnamon bark and generally used as a common food additive being antimicrobial against common postharvest pathogen such. Due to its touted benefit on cancer prevention, it can be hypothesized that cinnamic acid supports the immune system as well. [4] Cinnamic acid is a precursor to the sweetener aspartame via enzyme-catalysed amination to give phenylalanine. This site is part of the Natural News Network © 2012 All Rights Reserved. [8] The reactants for this are benzaldehyde and malonic acid in the presence of a weak base, followed by acid-catalyzed decarboxylation. Privacy | Terms All content posted on this site is commentary or opinion and is protected under Free Speech. [10], InChI=1S/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+, InChI=1/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+, Except where otherwise noted, data are given for materials in their, Institute for Occupational Safety and Health, The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals, Ullmann's Encyclopedia of Industrial Chemistry, "Zur Darstellung der Zimmtsäure und ihrer Homologen", "Determination of Abraham model solute descriptors for the monomeric and dimeric forms of, https://en.wikipedia.org/w/index.php?title=Cinnamic_acid&oldid=988839041, Wikipedia articles incorporating a citation from the 1911 Encyclopaedia Britannica with Wikisource reference, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License, This page was last edited on 15 November 2020, at 15:36. The acid is also a precursor to the sweetener aspartame. 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