blevy@igc.org Manganese, which enters the body primarily via inhalation, can damage the nervous system and respiratory tract, as well as have other adverse effects. View abstract. Some research has found that women with manganese levels that are too high or too low might have a higher chance of delivering male infants with a low birth weight. Manganese is an essential nutrient for humans and animals. Manganese is a naturally-occurring element that can be found ubiquitously in the air, soil, and water. Manganese is reactive when pure, and as a powder it will burn in oxygen, it reacts with water (it rusts like iron) and dissolves in dilute acids. There is no daily recommended intake of manganese, but the Adequate Intake (AI) is 2.3 milligrams (mg) per day for adult men and 1.8 mg per day for adult women. 2009;14(8):1180-1187. It also plays a … © 2005 - 2019 WebMD LLC. Schuh MJ. Increased manganese intake can cause the following harmful effects: However, too much manganese in the water supply can be toxic. People should talk to their healthcare provider before taking manganese supplements. Davidsson, L., Cederblad, A., Lonnerdal, B., and Sandstrom, B. Too much manganese triggers oxidative stress, inflammation, as well as cognitive and reproductive issues. View abstract. Dobson AW, Erikson KM, Aschner M. Manganese neurotoxicity. However, people who have trouble getting rid of manganese from the body, such as people with liver disease, may experience side effects when taking less than 11 mg per day.. The daily ULs for manganese are: for adults 19 years and older (including pregnant and breast-feeding women), 11 mg. Benevolenskaia, L. I., Toroptsova, N. V., Nikitinskaia, O. However, people do not usually need to take supplements to reach their daily AI of manganese. JPEN J Parenter.Enteral Nutr 1990;14(4):428-430. Taking manganese supplements may help a person with diabetes produce more insulin naturally, but more research in humans is necessary to confirm these effects. Gerber, G. B., Leonard, A., and Hantson, P. Carcinogenicity, mutagenicity and teratogenicity of manganese compounds. Antioxidants shield the body from free radicals, which are molecules that destroy or damage cells in the body. It is unclear if taking manganese alone has an effect on weight. It also plays a role in bone formation, blood clotting, and reducing inflammation. Ann N Y Acad Sci 2004;1012:115-28. Early research shows that taking manganese along with calcium helps improve symptoms of PMS, including pain, crying, loneliness, anxiety, restlessness, irritability, mood swings, depression, and tension. This is because manganese competes with iron for absorption. All information will be used in a manner consistent with the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter. Here are 5 major functions of manganese along with how they can create havoc when imbalanced: 1. Studies have shown that a high content of manganese in drinking water may lead to complications such as intellectual damage as well as a reduced intelligence quotient (IQ) among children who are of school age. AbstractManganese, which enters the body primarily via inhalation, can damage the nervous system and respiratory tract, as well as have other adverse effects. Early research shows that giving manganese, selenium, and zinc intravenously (by IV) may help people with worsened COPD to breathe on their own without help from a machine sooner. Learn more here. Freeland-Graves JH, Turnlund JR. 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