diarrhea. Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. Attacks many metals in the presence of water. Chronic: It has a role as a human xenobiotic metabolite. Phthalic acid is one of three isomers of benzenedicarboxylic acid, the others being isophthalic acid and terephthalic acid. They react in this way with all bases, both organic (for example, the amines) and inorganic. this substance have not been fully investigated. May cause skin irritation. Empirical Formula (Hill Notation) C 8 H 4 O 3. Incompatible materials: Strong acids, strong bases, strong oxidizing agents, strong reducing agents. Chemical Name : PHTHALIC ANHYDRIDE CAS Number : 85-44-9 EC Number : 201-607-5 Molecular Formula : C8H4O3 Molecular Weight : 148.1 Synonyms : Phthalic Acid Anhydride, 1,3-Isobenxofurandione, 1,2 Benzene Carboxylic Acid Anhydride Thermal decomposition can lead to release of irritating gases and vapors. 1,2-Benzenedicarboxylic acid, 3-nitro-3-nitro phthalic acid. 1,2-benzenedicarboxylic acid.....81 A.1.2.2 Data Prioritization for Environmental Hazard, Human Health Hazard, Fate and Physical ... Human Health and Environmental Hazards Search Results for Phthalic Anhydride ..... 25 Figure 2-11. Specific Hazards Arising from the Chemical Fine dust dispersed in air may ignite. The toxicological May cause respiratory tract irritation. Skin: Appearance: white crystals. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Phthalic acid is very soluble in boiling water, 18 g/100 mL, and is much less soluble in chilled (14°C) water, 0.54 g/100 mL. Inhalation: Phthalic acid is an aromatic dicarboxylic acid, with formula C 6 H 4 (CO 2 H) 2. 3-nitrobenzene-1,2-dicarboxylic acid. Phthalic acid, also called 1, 2-benzenedicarboxylic Acid, colourless, crystalline organic compound ordinarily produced and sold in the form of its anhydride. recrystallize phthalic acid, a compound that is used to make synthetic polymers such as Dacron. Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. Breakdown of all 141 C&L notifications submitted to ECHA © ILO and WHO 2017. Physical dangers View information & documentation regarding Phthalic acid, including CAS, MSDS & more. Outline the steps of the following procedure. Health Hazard. Commission Regulation (EU) No 2015/830 of 28 May 2015. In high concentrations, it can cause narcosis. NSC3120. Phthalic Acid Section 1: Identification of the substance/mixture and of the company / undertaking 1.1 Product Identifier Product Name Phthalic Acid Other Names Benzene-1,2-Dicarboxylic Acid CAS No. Effects of long-term or repeated exposure. 3-Nitrophthalic acid, 95%. This generates explosion hazard. Decomposes on contact with hot water. 201-873-2 Product Code S0001842 1.2 Relevant identified uses of the substances or mixture and uses advised against Phthalic anhydride ACS reagent, â¥99% CAS Number 85-44-9. : 88-99-3 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratorychemicals, Industrial & for professional use only. The toxicological properties of this substance have not Avoid dust formation and control ignition sources. NSC 3120. Irritating to eyes, respiratory system and skin. If heated, dust or fume may May cause gastrointestinal irritation with nausea, vomiting and Physical State; Appearance phthalic acid, copper salt Score: #495 in Physics , #1252 in Biology , #1446 in Chemistry It is an isomer of isophthalic acid and terephthalic acid. Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. phthalic acid - self classification Implementation: EU Remarks: self classification according to Directive 67/548/EEC Related composition Related composition: Composition 2 Classification open all close all. EINECS 210-030-8. m-Nitrophthalic acid. Chemical dangers Phthalic acid is an aromatic dicarboxylic acid, with formula C6H4(CO2H)2. Decomposes at 191°CRelative density (water = 1): 1.6 Solubility in water, g/100ml at 25°C: 0.625 (poor)Relative vapour density (air = 1): 5.7 Flash point: 168°C c.c.Octanol/water partition coefficient as log Pow: 0.73. A recent food safety concern has arisen from the unapproved use of certain phthalates in a broad range of food/nutraceutical ingredients from Taiwan [53]. Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. It is an isomer of isophthalic acid and terephthalic acid. Effects of short-term exposure Phthalic acid esters (phthalates) have been used as industrial plasticizers in a wide range of consumer products. Phthalic acid is a benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions. Phthalic acid Hazards. Rinse and then wash skin with water and soap. It is an isomer of isophthalic acid and terephthalic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. Phthalic acid esters are documented to accumulate irreversibly in organisms, of which DBP has been reported to exhibit not only carcinogenesis in diverse aquatic animals and hydrophytes but also adverse effects on male reproductive systems, leading to threats to the freshwater ecosystem. Hazards Identification. CRYSTALLINE POWDER. MFCD00007138. Sigma-Aldrich offers a number of Phthalic acid products. Eye: The substance is irritating to the eyes, skin and respiratory tract. Closed system, dust explosion-proof electrical equipment and lighting. Please contact Fisher Scientific for shipping information. Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance causes serious eye irritation, is harmful if swallowed, causes skin irritation and may cause respiratory irritation. The toxicological properties of Phthalic acid According to Regulation (EC) No 1907/2006, Annex II, as amended. This can happen as a direct influence on the synthesis of male hormones called androgens. SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Thus, water is a very good recrystallization solvent for phthalic acid. Product name : Phthalic Acid CAS-No. Phthalic acid is an aromatic dicarboxylic acid, with formula C6H4(CO2H)2. PubChem Substance ID 24859242. Sweep spilled substance into covered containers. Dust explosion possible if in powder or granular form, mixed with air. ... Reacts with moisture to give phthalic acid, which can corrode metals liberating hydrogen. 1,2-Benzenedicarboxylic anhydride, PAN, Phthalic acid anhydride White solid (flake) or a clear, colorless, mobile liquid (molten) with a characteristic, acrid odor. May cause eye and skin irritation. Prepared by an international group of experts on behalf of ILO and WHO, A nuisance-causing concentration of airborne particles can be reached quickly when dispersed, especially if powdered. PHTHALIC ANHYDRIDE reacts exothermically with water. Not listed EC No. NO open flames. Rinse with plenty of water for several minutes (remove contact lenses if easily possible). In primate Phthalic orally observed change in the levels of sex hormones. 210-211 °C (Decomposes) SynQuest 205 °C (Decomposes) Alfa Aesar 210 °C Jean-Claude Bradley Open Melting Point Dataset 14144: 230 °C Jean-Claude Bradley Open Melting Point Dataset 16989, 28454: 205 °C (Decomposes) Alfa Aesar 41770, A14450 210-211 °C (Decomposes) SynQuest 52322, 210-211 °C (Decomposes, Literature) LabNetwork LN00194231 204-209 °C LabNetwork LN00194231 88-99-3 Index No. Finely dispersed particles form explosive mixtures in air. The reactions are sometimes slow, but can become violent when local heating accelerates their rate. NACRES NA.21 Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a ⦠Use water spray, powder, alcohol-resistant foam, carbon dioxide. CDC - NIOSH Pocket Guide to Chemical Hazards - Phthalic anhydride Combustible. If appropriate, moisten first to prevent dusting. It is an isomer of isophthalic acid and terephthalic acid. cause respiratory tract irritation. May cause eye irritation. properties of this material have not been fully investigated. ISOPHTHALIC ACID is a carboxylic acid. This produces phthalic acid. Phthalic acid (PA) is chemical substance that is an aromatic dicarboxylic acid, with the chemical formula C 6 H 4 (COOH) 2.It is used primarily to make corrosion inhibitors that are applied to metal substrate surfaces. 3-Nitrophthalicacid. 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd 7/28 Vardaan House New Delhi-10002 INDIA Phthalic anhydride reaction on human health is generally an asthma-rhinitis-conjunctivitis syndrome or a delayed reaction and influenza-like symptoms and with increased immunoglobulin (immunoglobulin E, immunoglobulin G) levels in the blood. ACUTE/CHRONIC HAZARDS: This compound is an irritant of the skin, eyes, mucous membranes, and respiratory tract. As part Wash away remainder with plenty of water. Inhalation: Inhalation of vapor, fume or dust is a primary irritant. Acids accelerate the reaction with water. 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